Endocrine Abstracts

Introduction: Anaplastic thyroid carcinoma (ATC) is the most aggressive and invasive histological type of thyroid carcinomas. Frequently, upon diagnosis obstructive symptoms and loco-regional metastasis have already occurred. Presence of distant metastasis in the skeletal muscle in ATC is rare; and there are less than five documented cases reported worldwide.Case: A 68-year-old Filipino Male, presents with two-month history of pain on the right thigh. He...

Background: Patients with complete androgen insensitivity syndrome (CAIS) who undergo gonadectomy have evidence of reduced bone mineral density (BMD) and perhaps, higher risk of fragility fractures. Because of this, hormonal replacement therapy (HRT), usually in the form of estrogen, is used as patients with CAIS have 46, XY genotypes having androgen receptor abnormalities making them resistant to the effects of androgen. Tibolone, a “selective tissue estrogenic activity...